An experimental drug called, JD5037 has been tested in mice, and is showing promise to one day help people lose weight and keep it off long-term. This according to a study in the July issue of the journal Cell Metabolism.
The drug increases sensitivity to the hormone leptin, which is a natural appetite suppressant found in the body. In the study, the researchers found that JD5037 suppressed the appetite of obese mice which led to their weight loss.
Senior study author, George Kunos the U.S. National Institute on Alcohol Abuse and Alcoholism, said that the new drug could maintain the weight loss in addition to promoting it.
According to the release, Leptin supplements alone may not be helpful at assisting patients to lose excess weight. It’s theorized that this is due to desensitization to leptin, which means that the body can no longer respond to it.
According to the Centers for Disease Control over 35 percent of U.S. adults are obese. The states with the highest rates of obesity stretch from Texas, east to South Carolina and north to Kentucky with a state-wide obesity rate greater than 30 percent.
Approximately 17 percent of children and adolescents aged 2—19 years are obese. The number of obese children has tripled since 1980.
Obesity can cause heart disease, stroke, type 2 diabetes and certain types of cancer, all of these are leading causes of death in the United States.
There is no magic elixir for losing weight, and even if this treatment does show promise in humans it is years, and possibly decades away from being FDA approved. The most effective way to lose weight remains portion control of meals and regular exercise. While this is not new information, it is the best way to drop weight and get in better shape.
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